Research
Research approaches
We believe that the understanding of brain mechanisms underlying neuropsychiatric disorders can be best achieved using a multidisciplinary approach. Therefore, we combine behavioral, molecular and biochemical approaches.
- In vivo intra-cerebral manipulation and psychopharmacology: Systemic and intra-cerebral pharmacology; Stereotaxic brain surgeries; Viral-mediated gene delivery; In vivo optogenetic stimulation; Histology.
- Behavior: Animal models of moderate and excessive drug/alcohol self-administration, relapse, and drug reward; Assessment of motivational and emotional factors in drug consumption; Animal models of learning and memory.
- Biochemistry and molecular biology: DNA, RNA and protein assays, immunohistochemistry, immunofluorescence and microscopy.
Projects in the lab include:
- Erasure of drug-related memories to prevent relapse to drug seeking and consumption
- Role of epigenetic processes in the development of psychiatric disorders
- Role of growth factors in learning and memory processes in addiction
- Molecular mechanisms in memory consolidation and reconsolidation